Larson, B., M. Van, T. Nakayama and J. Engebrecht (2016) Plasticity of the meiotic epigenetic landscape of sex chromosomes in Caenorhabditis species. Genetics 203, 1641-1658. [full text]

Lawrence, K.S., T. Chau and J. Engebrecht (2015) DNA Damage Response and Spindle Assembly Checkpoint function throughout the cell cycle to ensure genomic integrity PlosGenetics 11(4):e1005150. [full text]

Checchi, P., K. Lawrence, M. Van, B. Larson and J. Engebrecht (2014) Pseudosynapsis and decreased stringency of meiotic repair pathway choice on the hemizygous sex chromosome of Caenorhabditis elegans males. Genetics 197, 543-560. [full text]

Lawrence, K. and J. Engebrecht (2012). Slowing replication in preparation for reduction. PlosGenetics 8(5):e1002715. [full text]

Checchi, P. and J. Engebrecht (2011) C. elegans histone methyltransferase MET-2 shields the male X chromosome from checkpoint machinery and mediates meiotic sex chromosome inactivation. PlosGenetics 7:e1002267. [full text]

Checchi, P. and J. Engebrecht (2011) Heteromorphic sex chromosomes: Navigating meiosis without a homologous partner. Mol. Repro. Dev. 78, 623-632. [full text]

Jaramillo-Lambert, A., Y. Harigaya, J. Vitt, A, Villeneuve, and J, Engebrecht (2010). Meiotic errors activate checkpoints that improve gamete quality without triggering apoptosis in male germ cells. Curr Biol 20, 2078-2089. [full text]

Comment in: Curr Biol. 2010 20:R1014-1016. [full text]

Jaramillo-Lambert, A. and J. Engebrecht (2010). A single unpaired and transcriptional silenced X  chromosome locally precludes checkpoint signaling in the Caenorhabditis elegans germ line. Genetics 184, 613-628. [full text]

Jaramillo-Lambert, A., M. Elefson, A. Villeneuve, and J. Engebrecht (2007). Differential timing of S phases, X chromosome replication and meiotic progression in the C. elegans germline. Dev. Biol. 308,206-221.[full text]

Smolikov, S., A. Eizinger, K. Schild-Prufert, A. Hurlburt, K. McDonald, J. Engebrecht, A. M. Villeneuve, M. P. Colaiacovo (2007) SYP-3 restricts synaptonemal complex assembly to bridge paired chromosome axes during meiosis in Caenorhabditis elegans. Genetics 176, 2015-2025. [full text]

Publications on Yeast Meiosis & Sporulation

Mendonsa R, Engebrecht J (2009) Phosphatidylinositol-4,5-bisphosphate and phospholipase D-generated phosphatidic acid specify SNARE-mediated vesicle fusion for prospore membrane formation. Eukaryot Cell 8: 1094-1105.

Mendonsa R, Engebrecht J (2009) Phospholipase D function in Saccharomyces cerevisiae. Biochim Biophys Acta 1791: 970-974.

Morishita M, Engebrecht J (2008) Sorting signals within the Saccharomyces cerevisiae sporulation-specific dityrosine transporter, Dtr1p, C terminus promote Golgi-to-prospore membrane transport. Eukaryot Cell 7: 1674-1684.

Morishita M, Mendonsa R, Wright J, Engebrecht J (2007) Snc1p v-SNARE transport to the prospore membrane during yeast sporulation is dependent on endosomal retrieval pathways. Traffic 8: 1231-1245.

Nakanishi H, Morishita M, Schwartz CL, Coluccio A, Engebrecht J, et al. (2006) Phospholipase D and the SNARE Sso1p are necessary for vesicle fusion during sporulation in yeast. J Cell Sci 119: 1406-1415.

Connolly JE, Engebrecht J (2006) The Arf-GTPase-activating protein Gcs1p is essential for sporulation and regulates the phospholipase D Spo14p. Eukaryot Cell 5: 112-124.

Morishita M, Engebrecht J (2005) End3p-mediated endocytosis is required for spore wall formation in Saccharomyces cerevisiae. Genetics 170: 1561-1574.

Iwamoto MA, Fairclough SR, Rudge SA, Engebrecht J (2005) Saccharomyces cerevisiae Sps1p regulates trafficking of enzymes required for spore wall synthesis. Eukaryot Cell 4: 536-544.

Rudge SA, Sciorra VA, Iwamoto M, Zhou C, Strahl T, et al. (2004) Roles of phosphoinositides and of Spo14p (phospholipase D)-generated phosphatidic acid during yeast sporulation. Mol Biol Cell 15: 207-218.

Engebrecht J (2003) Cell signaling in yeast sporulation. Biochem Biophys Res Commun 306: 325-328.

Rudge, S., C. Zhou and J. Engebrecht (2002). Differential regulation of phospholipase D during sporulation and Sec14-independent growth in Saccharomyces cerevisiae. Genetics 160, 1353-1361.

Sciorra, V., S. Rudge, J. Wang, S. McLaughlin, J. Engebrecht and A. Morris (2002). Dual role for phosphoinositides in regulation of yeast and mammalian phospholipase D enzymes. J. Cell Biol. 159, 1039-1049.

Rudge, S., T. Pettitt, C. Zhou, M. Wakelam and J. Engebrecht (2001). SPO14 Separation-of-function mutations define unique roles for PLD in secretion and cellular differentiation. Genetics 158, 1431-1444. (PMC1461740)

Davis, L., M. Barbera, A. McDonnell, K. McIntyre, R. Sternglanz, Q.-W. Jin, J Loidl and J. Engebrecht (2001). The Saccharomyces cerevisiae MUM2 gene interacts with the DNA replication machinery and is required for meiotic levels of DSBs. Genetics 157, 1179-1180. (PMC1461570)

Heymont, J., L. Berenfeld, J. Collins, A. Kaganovich, B. Maynes, B. Maynes, A. Moulin, I. Ratskovskaya, P. P. Poon, G. C. Johnston, M. Kamesetsky, J. DeSilva, G. A. Petsko, H. Sun, and J. Engebrecht (2000). TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation. Proc. Natl. Sci. USA 97, 12672-12677. (PMC18822)

Sciorra, V. A., S. A. Rudge, G. D. Prestwich, M. A. Frohman, J. Engebrecht, and A. J. Morris (1999). Identification of a phosphoinositide binding motif that mediates activation of yeast and mammalian phospholipase D isoenzymes. EMBO J. 18, 5911-5921.

Rudge, S. A., A. Morris, and J. Engebrecht (1998). Relocalization of phospholipase D mediates membrane formation during meiosis. J. Cell Biol. 140, 81-90.

Davis, L., and J. Engebrecht (1998). Yeast dom34 mutants are defective in multiple developmental pathways and exhibit decreased levels of polyribosomes. Genetics 149, 45-56.

Rudge, S. A., M. M. Cavenagh, R. Kamath, V. A. Sciorra,  A. J. Morris, R. A. Kahn, and J. Engebrecht (1998). ADP-Ribosylation factors do not activate yeast phospholipase D, but are required for sporulation.  Mol. Biol. Cell 9, 2025-2036.

Xie, Z., M. Fang, A. J. Faulkner, P. C. Sternweis, J. Engebrecht, and V. A. Bankaitis (1998). Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein. Proc. Natl. Acad. Sci. USA 95, 12346-1235.

Engebrecht, J., S. Masse, L. Davis, K. Rose, and T. Kessel (1998). Yeast meiotic mutants proficient for the induction of ectopic recombination. Genetics 148, 581-598.

Rudge, S. A., A. Morris, and J. Engebrecht (1998). Relocalization of phospholipase D mediates membrane formation during meiosis. J. Cell Biol. 140, 81-90. (PMC2132601)

Sung, T.-C., R. Roper, Y. Zhang, S. A. Rudge, R. Temel, S. M. Hammond, A. Morris, B. Moss, J. Engebrecht, and M. Frohman (1997). Mutagenesis of phospholipase D defines a superfamily including a trans-Golgi viral protein required for poxvirus pathogenicity. EMBO J. 16, 4519-4530.

Hammond, S. M., Y. M. Altshuller, T.-C. Sung, S. A. Rudge, K. Rose, J. Engebrecht, A. J. Morris, and M. A. Frohman (1995). Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family. J. Biol. Chem. 270, 29640-29643.

Rose, K., S. A. Rudge, M. A. Frohman, A. J. Morris, and J. Engebrecht (1995). Phospholipase D signaling is essential for meiosis. Proc. Natl. Acad. Sci. USA 92, 12151-12155. (PMC40314)

Rockmill, B., J. Engebrecht, H. Scherthan, J. Loidl, and G. S. Roeder (1995). The yeast MER2 gene is required for chromosome synapsis and the initiation of meiotic recombination. Genetics 141, 49-59.

Sym, M., J. Engebrecht, and G. S. Roeder (1993). ZIP1 is a structural component of the synaptonemal complex. Cell 72, 365-378.

Bhargava, J., J. Engebrecht, and G. S. Roeder (1992). The rec102 mutant of yeast is defective in meiotic recombination and chromosome synapsis. Genetics 130, 59-69.

Engebrecht, J., K. Voelkel-Meiman, and G. S. Roeder (1991). Meiosis-specific RNA splicing in yeast. Cell 66, 1257-1268.

Engebrecht, J., J. Hirsch, and G. S. Roeder (1990). Meiotic gene conversion and crossing over: Their relationship to each other and to chromosome synapsis and segregation. Cell 62, 927-937.

Engebrecht, J., and G. S. Roeder (1990). MER1, a yeast gene required for chromosome pairing and genetic recombination, is induced in meiosis. Mol. Cell. Biol. 10, 2379-2389.

Engebrecht, J., and G. S. Roeder (1989). Yeast mer1 mutants display reduced levels of meiotic recombination. Genetics 121, 237-247.